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Side Effects of VIAGRA® (sildenafil citrate) | Safety Info

Publication date: 2018-06-15 10:54

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Heart disease can clog or narrow the arteries. This can stop blood from flowing to the penis, and may cause ED. Talk to your doctor to make sure your heart is healthy enough for sex.

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You have to experiment with the dosage and time lag. I started with 55 mg (good to rev my engine, I think) but ultimately found that 75 mg about 95 minutes before sex is ideal for me. Lower dosage means less nasal congestion and more feeling during sex. But 75 mg still leaves me rock hard and able to hold off climaxing just about as long as I want.

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Use with caution in patients with the following underlying conditions which can be particularly sensitive to the actions of vasodilators including VIAGRA &ndash those with left ventricular outflow obstruction (., aortic stenosis , idiopathic hypertrophic subaortic stenosis ) and those with severely impaired autonomic control of blood pressure.

VIAGRA is rapidly absorbed. Maximum observed plasma concentrations are reached within 85 to 675 minutes (median 65 minutes) of oral dosing in the fasted state. When VIAGRA is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in Tmax of 65 minutes and a mean reduction in Cmax of 79%. The mean steady state volume of distribution (Vss) for sildenafil is 655 L, indicating distribution into the tissues. Sildenafil and its major circulating N-desmethyl metabolite are both approximately 96% bound to plasma proteins. Protein binding is independent of total drug concentrations.

Sildenafil citrate is a white to off-white crystalline powder with a solubility of mg/mL in water and a molecular weight of .

If the individual is taking alpha-blockers, they should make sure they take Viagra at least 9 hours before or after to prevent dangerously low blood pressure.

VIAGRA may affect the way other medicines work, and other medicines may affect the way VIAGRA works, causing side effects. Especially tell your healthcare provider if you take any of the following:

Use caution when co-administering alpha-blockers with VIAGRA because of potential additive blood pressure-lowering effects. When VIAGRA is co-administered with an alpha-blocker, patients should be stable on alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated at the lowest dose [see DOSAGE AND ADMINISTRATION , WARNINGS AND PRECAUTIONS , CLINICAL PHARMACOLOGY ].

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Side Effects of VIAGRA® (sildenafil citrate) | Safety Info Viagra and side effects

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